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Generated February 18, 2018

Acetylenes disubstituted with a 5 substituted tetrahydronaphthyl group and with an aryl or heteroaryl group having retinoid-like biological activity

Patent Number: 5,605,915

Patent Information

Abstract
Compounds of the formula ##STR1## wherein the symbols have the meaning defined in the specification.
Patent Number: 5,605,915
Issue Date: 1997-02-25

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Citations

Patents that cite this patent

Patent Title
8,815,954 Arginine heteromers for topical administration
8,628,756 Arginine heteromers for topical administration
8,013,001 Modulators of LXR
7,998,986 Modulators of LXR
7,537,841 Method and process to reduce surface cracking for coated hardwood composite flooring
7,476,673 Disubstituted chalcone oximes as selective agonists of RAR
7,381,474 Coated hardwood composite flooring having reduced surface cracking
7,253,319 Disubstituted chalcone oximes having RARγ retinoid receptor antagonist activity
7,166,726 Aryl substituted 3,4-dihydroanthracene derivatives having retinoid antagonist or retinoid inverse agonist type biological activity
6,942,980 Methods of identifying compounds having nuclear receptor negative hormone and/or antagonist activities
6,855,832 O- or S-substituted tetrahydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity
6,818,775 Alkyl or aryl substituted dihydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity
6,720,425 Alkyl or aryl substituted dihydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity
6,660,755 Substituted diaryl or diheteroaryl methans, ethers and amines having retinoid agonist, antagonist or inverse agonist type biological activity
6,653,483 Alkyl or aryl substituted dihydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity
6,555,690 Alkyl or aryl substituted dihydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity
6,538,149 ARYL OR HETEROARYL SUBSTITUTED 3,4-DIHYDROANTHRACENE AND ARYL OR HETEROARYL SUBSTITUTED BENZO |1,2-G|CHROM-3-ENE, BENZO|1,2-G|-THIOCHROM-3-ENE AND BENZO |1,2-G|-1,2-DIHYDROQUINOLINE DERIVATIVES HAVING RETINOID ANTAGONIST OR RETINOID INVERSE AGONIST TYPE BIOLOGICAL ACTIVITY
6,521,624 Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities
6,469,028 Synthesis and use of retinoid compounds having negative hormone and/or anatgonist activities
6,455,701 Substituted diaryl or diheteroaryl methanes, ethers and amines having retinoid agonist, antagonist or inverse agonist type biological activity
6,437,129 Substituted aryl or heteroarylamides having retinoid-like biological activity
6,344,561 O- or S- substituted tetrahydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity
6,344,463 Disubstituted acetylenes bearing heterobicyclic groups and heteroaromatic or phenyl groups having retinoid like activity
6,342,602 Aryl or heteroaryl amides of tetrahydronaphthalene, chroman, thichroman and 1,2,3,4-tetrahydroquinolinecarboxlic acids, having an electron withdrawing substituent in the aromatic or heteroaromatic moiety, having retinoid-like biological activity
6,320,047 Substituted aryl or heteroarylamides having retinoid-like biological activity
6,313,163 2,4-pentadienoic acid derivatives having retinoid-like biological activity
6,245,786 Substituted aryl or heteroarylamides having retinoid-like biological activity
6,235,923 Trisubstituted phenyl derivatives having retinoid agonist, antagonist or inverse agonist type biological activity
6,228,848 Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities
6,225,494 Trisubstituted phenyl derivatives having retinoid agonist or inverse agonist type biological activity
6,218,128 Methods of identifying compounds having nuclear receptor negative hormone and/or antagonist activities
6,187,950 Substituted diaryl or diheteroaryl methanes, ethers and amines having retinoid agonist, antagonist or inverse agonist type biological
6,187,933 O- or S- substituted tetrahydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity
6,124,455 Aryl or heteroaryl amides of tetrahydronaphthalene, chroman, thiochroman and 1,2,3,4-tetrahydroquinoline carboxylic acids, having an electron withdrawing substituent in the aromatic or heteroaromatic moiety, having retinoid-like biological activity
6,117,987 Alkyl or aryl substituted dihydronaphthalene derivatives having retinoid and/or retinoid antagonist like biological activity
6,114,533 2,4-pentadienoic acid derivatives having retinoid-like biological activity
6,090,826 Disubstituted acetylenes bearing heterobicyclic groups and heteroaromatic or phenyl groups having retinoid like activity
6,090,810 Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities
6,087,505 Benzo[1,2-G]-chrom-3-ene, and benzo[1,2-G]-thiochrom-3-ene derivatives
6,051,731 O-or S-substituted tetrahydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity
6,051,713 Substituted aryl or heteroarylamides having retinoid-like biological activity
6,037,488 Trisubstituted phenyl derivatives having retinoid agonist, antagonist or inverse agonist type biological activity
6,034,242 2,4-pentadienoic acid derivatives having retinoid-like biological activity
6,008,204 Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities
5,998,655 Alkylidene substituted tetrahydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity
5,998,471 Acetylenes disubstituted with a 5 alkyl, aryl or heteroaryl substituted dihydronaphthyl group and with an aryl or heteroaryl group having retinoid-like biological activity
5,958,954 Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities
5,952,345 Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities
5,919,970 Substituted diaryl or diheteroaryl methanes, ethers and amines having retinoid agonist, antagonist or inverse agonist type biological activity
5,917,082 2,4-pentadienoic acid derivatives having retinoid-like biological activity
5,917,048 Substituted aryl or heteroarylamides having retinoid-like biological activity
5,856,490 Aryl or heteroaryl amides of tetrahydronaphthalene, chroman, thiochroman and 1,2,3,4-tetrahydroquinoline carboxylic acids, having an electron withdrawing substituent in the aromatic or heteroaromatic moiety, having retinoid-like biological activity
5,847,160 Acetylenes disubstituted with 2-tetrahydropyranoxy-aryl and aryl of heteroaryl groups having retinoid-like biological activity
5,817,836 2,4-pentadienoic acid derivatives having retinoid-like biological activity
5,808,083 Acetylenes disubstituted with a 5 alkyl, aryl or heteroaryl substituted dihydronaphthyl group and with an aryl or heteroaryl group having retinoid-like biological activity
5,760,276 Aryl-and heteroarylcyclohexenyl substituted alkenes having retinoid agonist, antagonist or inverse agonist type biological activity
5,750,693 Disubstituted acetylenes bearing heterobicyclic groups and heteroaromatic or phenyl groups having retinoid like activity
5,728,846
5,677,320 Phenyl or heteroaryl and tetrahydronaphthyl substituted diene compounds having retinoid like biological activity

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